Saturday, January 8, 2011

Question 1

Explain how the ebola virus multiplies. Be sure to cite sources if needed.

14 comments:

  1. The ebola virus multiplies extreamly fast. The virus clings on to any and every cell it can. It then gets inside the cell and multiplies making the cell a 'brick' packed with the virus ready to explode. The infected cell drifts into the blood strem and the virus laches onto more cells. More and more cells in the blood stream become infected with ebola. This contuines until even the smallest dropof blood contains around '1 million indviual particals'

    Hayley Parenti Period 2

    Work cited;

    http://cydathria.com/ebola.html

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  2. Hayley nice post, but try and tell me how the virus goes from being one particle to 1 million.

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  3. Ebola has not been proven to multiply through the air although it is very contagious. Ebola causes non stop bleeding and very high fevers. This virus is called a filovirus. I could not find the places in the book where the described how the cells pass the virus so i did some research. A filovirus wants to target the cells. in the beginning of this process the virus goes for macrophages. The macrophages carry the virus from the infected part through the lymph system. After this the virus is able to go through the body and hit the organs. Ebola cells are 'brick' cells becuase they have so much virus in one cell. When the cells burst the virus comes out. This virus basically deterierates all organs until they cannot live.


    abby painchaud period one

    http://www.ukessays.com/essays/biology/filoviridae.php

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  4. The ebola Virus is highly contagious,althoug it has not been proven exactly how it is transmitted.The ebola virus multiplies by infecting individual cells. The virus infects the cells and start producing copies of itself, which then go out through your body infecting other cells. The infected cells become crystal like blocks packed with virus particles. The particles push through the cell wall and are released into your blood stream. The virus attacks your organs and tisues, multipling until most of the cells are crystal blocks full of ebola.
    This whole procces can start with just one virus cell. This cell starts a chain reaction that infects other cells, which then release the vrus to infect more cells. Once the vurs has infected most of the body, your organs shut down and you die. Unless the virus can infect another host before this though, it dies with you.

    James Osborne Period 2

    http://cydathria.com/ebola.html
    http://www.sciencedigest.org/EBOLA.HTM

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  5. Is there a certain organ that mor ebola is found in?

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  6. It is known by USAMRIID that the Ebola virus is spread through direct sexual or blood to blood contact, just like AIDS. In the book, people in Africa were becoming quickly infected by dirty, reused needles and by handling dead Ebola victims. Later on, it is also questioned whether or not the virus could be spread through the air. Once a person is infected with Ebola, it multpilies unknowingly for 3-21 days, during an incubation period. During this time, similarly to HIV, the Ebola virus attacks the immune cells in the body. This attack on white blood cells further allows the virus to multiply viciously throughout all parts of the body. It can travel anywhere from the liver, spleen, lungs and even the brain. To answer your question Mrs. Mailhot, the scientist at USAMRIID analyze cells from infected monkeys' livers. This is presumably because the virus is found here in the densest amounts. It shows how the massive amount multiplies very rapidly in the liver sample on page 150 where Tom Geisbert describes what he thought was "pepper" as bricks full of virus. This evidence illustrates the speed of Ebola multiplication. Also, Tom's fear shows that he is well aware of how contagious this virus is. He knows that once the cell bursts, all of the virus will flow out to infect even more cells. The Ebola virus multiplies rapidly and efficiently from cell to cell.

    Meagan Olive Period 1

    http://ebola.emedtv.com/ebola/ebola-incubation-period.html

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  7. The Ebola virus is the most commonly found in the liver because when they were dissecting the monkeys this is where they looked the most for the Ebola virus cells.

    Ebola is very dangerous, and it is called a filovirus. There is a 2-21 incubation period for this virus once it get's inside of your body. Ebola Zaire attacks every organ and tissue in the human body except skeletal muscle and bone.This parasite converts every organ in the body into slime almost. Ebola kills a great deal of tissue while the host is still alive. It triggers a creeping, spotty necrosis that spreads through all the internal organs. The liver bulges up and turns yellow, begins to liquefy, and then it cracks apart. Ebola (and Marburg) multiplies so rapidly and powerfully that the body's infected cells become crystal-like blocks of packed virus particles. Then, the cell bursts and the virus will flow out and infect even more cells, and so on, until the host is dead.

    http://cydarthia.com/ebola.html

    Kristen Perreault
    Period 4

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  8. Only one Ebola virus particle needs to get into a human’s blood to start multiplying and soon take over their body. Once the virus gets into a cell it immediately multiplies starting in the middle of the cell. It then works its way out to the edges. The cell becomes packed with a million virus particles. When the cell can’t hold any more of the virus and is packed like a brick, the virus breaks out and travels throughout the entire body destroying every tissue. Leaving only bones and muscles untouched. Scientists have noticed a majority of the virus in its host’s liver, and the spleen becomes one big blood clot. The virus causes any hole in the body to spill blood and the skin tears and bleeds incredibly easily.
    Holly Grace
    Mrs. Reardon
    Period 2

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  9. Mrs. Mailhot,
    I had posted here a few days ago with a lengthy post, but it never showed up. Were you able to see it, or do I need to re-post it?

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  10. This comment has been removed by the author.

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  11. Starting with just one particle of the virus entering someone’s body, primarily through blood-to-blood contact, the victim’s immune system goes into shock and is not able to produce enough white blood cells to fight off the new enemy. There is only a 50 to 10 percent chance that this infected body will survive from the encounter and infestation from this Ebola virus. Of the three strains of the Ebola virus mentioned in “The Hot Zone” – Zaire, Sudan, and Reston – only Zaire and Sudan are the strains that cause extreme disease in humans. All forms of Ebola are found in both humans and primates, such as chimps and apes, and cause turmoil in the cells of the victim. When a filovirus such as this – a virus which causes hemorrhagic fever – enters a person’s blood stream it quickly enters the cells of various organs in the body, and rapidly multiplies until the cell can no longer contain the virus particles. When it comes to this point the microscopic images of the infected cells have been described as “bricks” and the cell wall bursts, causing the virus to spread to a countless number of other cells in the body. The parts of the body which the Ebola virus spreads to are all of your organs and tissues, the liver being a haven for virus reproduction, but the bones and skeletal muscles are the only things not affected. Once a person is so extremely infected with the Ebola virus, their skin is very thin, and a major symptom is that they bleed out from all opening in the body and skin – the term for this used in the book is “crashing” – and this eventually leads to death. Ebola is a very contagious virus and rapidly multiplies within the body, causing the infected being to get sick within an incubation period of 2-21 days. In this time the virus destroys all cells until their host is no more.

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  12. ^
    Megan Reese
    Period 4

    Works cited:
    http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/filoviruses.htm

    http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/Fact_Sheets/Ebola_Fact_Booklet.pdf

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  13. The Ebola virus is an extremely destructive virus that infects the body and destroys every system of the body except for the muscular and bone systems. Ebola is known to be transmitted through body fluids (blood, organs, tissue, semen, vaginal secretions, etc.) and in Ebola Reston (a strain of Ebola) through the air. Once Ebola enters the body all it has to do is infect one cell. Ebola contains seven proteins. These seven proteins consume the host cell and allow the virus to begin to replicate. It has been recently found that Ebola also releases “enzyme-inhibiting chemicals” that allow the virus to grow. The virus replicates so quickly that it grows virus bricks. These virus bricks contain virus particles that push to the wall cell and then explode out of the cell, releasing hundreds of virus. The virus is released into the blood infecting every cell along the way. Almost all of the cells become infected. The body tissue becomes “saturated” with virus bricks. The virus kills most of the body tissue. The virus eventually attacks the structural protein of the body of the host. The internal structures of the host become soupy by the time they “crash-out”. Ebola is one of the hottest viruses. It multiplies so quickly that by the “amplification” of the virus there can be up to 100 million viruses in one drop of blood.
    1) http://hubpages.com/hub/Ebola-Virus-Lifecycle-and-Pathology

    2) http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/Fact_Sheets/Ebola_Fact_Booklet.pdf

    3) http://www.emaxhealth.com/24/1919.html
    Maddie Stewart-Boldin
    Period Four, Mailhot

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  14. Holly,good post. What was your source?
    So how can the virus reproduce if it is not living?
    Mrs. Reardon

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